The Caspase 3 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to CASP3, and Lice. This antibody recognizes Human antigen. The Caspase 3 Antibody has been validated for the following applications: Western Blot.
Description
Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-:-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin